Benjamin Kidder

projects

Faculty Profile

Assistant Professor
ff2646@wayne.edu

Position Title

Assistant Professor
Basic Science

Office Location

Karmanos Cancer Institute
HWCRC Rm 624

Mailing Address

 Karmanos Cancer Institute
4100 John R. Rd
Mailcode: HW06AO
Detroit, MI 48201

Office Phone

313-576-8302

Education Training

Education
(2002-2007)  Ph.D. Molecular, Cellular, Developmental Biology and Genetics (MCDB&G), University of Minnesota, Minneapolis, MN
(1997-2001)  B.A. Chemistry and Biology, Saint Olaf College, Northfield, MN

Postgraduate Training
(2012-2015)  Research Fellow, National Heart, Lung and Blood Institute, (NHLBI, NIH), Bethesda, MD
(2011-2012)  IRTA-Fellow, National Heart, Lung and Blood Institute (NHLBI, NIH), Bethesda, MD
(2007-2009)  Postdoctoral Fellow, EMD/Merck Serono Research Institute, Rockland, MA

Professional Experience

Faculty Appointments
(2015-Present)  Scientific Member, Tumor Biology and Microenviornment Program, Karmanos Cancer Institute, Detroit, MI
(2009-2011)  Principal Investigator, EMD/Merck Serono Research Institute, Rockland, MA

Major Professional Societies

(2013-2014)  American Society for Microbiology (ASM)
(2010-2012)  International Society for Stem Cell Research (ISSCR)
(2008-2009)  Society for the Study of Reproduction (SSR)
(2008-2010)  American Society for Reproductive Medicine (ASRM)

Honors and Awards

(2016) NHLBI Career Transition Award (K22), National Heart, Lung and Blood Institute, NIH, Bethesda, MD
(2015) NIH Fellows Award for Research Excellence (FARE) Winner, National Heart, Lung and Blood Institute, NIH, Bethesda, MD
(2014) Genome Engineering Technology Award, NHLBI, NIH, National Heart, Lung and Blood Institue
(2013) Performance Award, NHLBI, NIH, National Heart, Lung and Blood Institute, NIH, Bethesda, MD
(2010) EMD/Merck Serono Research Institute On-The-Spot Award, EMD/Merck Serono Research Institute, Rockland, MA
(2010) EMD/Merck Millipore Tech Expo Poster Award, EMD/Merck Millipore, Billerica, MA
(2004-2005) NIH NIGMS Biotechnology Training Grant, University of Minnesota, Minneapolis, MN
(2002) Award for Excellence, NIDCR, NIH, National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD
(2001-2002) Postbaccalaureate pre-IRTA Fellow at the NIH
(2001-2002) National Institute of Dental and Craniofacial Research, NIH, Bethesda, MD
(1998-2000) Finstad Grant Recipient/Entrepreneurs Club, St. Olaf College, Northfield, MN

Courses taught

CB 7210: Fundamentals of Cancer Biology
CB 7460: Mechanisms of Neoplasia - Alterations to Cellular Signaling
CB 7700: Recent Developments in Cancer Biology 

Publications

1.Kidder BL, Hu G, Zhao K. KDM5B focuses H3K4 methylation near promoters and enhancers during embryonic stem cell self-renewal and differentiation. GENOME BIOLOGY 2014 Feb 4;15(2):R32 (Epub).

2.Kidder BL, Zhao K. Efficient library preparation for next-generation sequencing analysis of genome-wide epigenetic and transcriptional landscapes in embryonic stem cells. METHODS IN MOLECULAR BIOLOGY. 2014;1150:3-20. doi: 10.1007/978-1-4939-0512-6_1.PMID:24743988

3. Kidder BL, Hu G, Yu Z, Liu C, Zhao K. Extended self-renewal and accelerated reprogramming in the absence of Kdm5b. MOLECULAR AND CELLULAR BIOLOGY 2013 Dec;33(24):4793-810. PMID: 24100015

4. Kidder BL, Palmer S. HDAC1 regulates pluripotency and lineage specific transcriptional networks in embryonic and trophoblast stem cells. NUCLEIC ACIDS RESEARCH 2012 Apr;40(7):2925-39. PMID: 22156375

5. Kidder BL, Hu G, Zhao K. ChIP-Seq: technical considerations for obtaining high quality data. NATURE IMMUNOLOGY 2011 Sep 20;12(10):918-22. PMID: 21934668

6. Kidder BL, Palmer S. Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance. GENOME RESEARCH 2010 Apr;20(4):458-72. PMID: 20176728

7. Kidder BL, Palmer S, Knott JG.  SWI/SNF-Brg1 regulates self-renewal and occupies core pluripotency-related genes in embryonic stem cells. STEM CELLS 2009 FEB; 27(2):317-28. PMID: 19056910

8. Kidder BL, Yang J, Palmer S. Stat3 and c-Myc genome-wide promoter occupancy in embryonic stem cells. PLOS ONE. 2008;3(12):e3932 PMID: 19079543

9. Kidder BL, Oseth L, Miller SC, Hirsch B, Verfaillie C, Coucouvanis E. Embryonic stem cells contribute to mouse chimeras in the absence of detetable cell fusion. CLONING STEM CELLS 10 (2): 231-248 JUN 2008. PMID: 18338954

10.Ulloa-Montoya F*, Kidder BL*, Pauwelyn K, Chase L, Luttun A, Crabbe A, Geraerts M, Sharov AA, Piao Y, Ko MS, Hu WS, Verfaillie CM. Comparative transcriptome analysis of embryonic and adult stem cells with extended and limited differentiation capacity. GENOME BIOLOGY 8 (8): R163 2007.PMID: 17683608

 * authors contributed equally

Faculty Status

Basic Science

Research Description

• Stem cell Epigenetics
• Transcriptional Networks
• Reprogramming and Transdifferentiation
• Genome Stability

Affiliated Departments

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