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M.P.H., M.D. , F.A.C.P.
Office Location
EACPHS, Room 2156
Phone
313-577-1215
Biography
Dr. Paul Kilgore is a Professor in the Department of Pharmacy Practice at Wayne State University's Eugene Applebaum College of Pharmacy and Health Sciences and Co-Director of the Center for Emerging and Infectious Diseases at Wayne State University School of Medicine.
Dr. Kilgore received his MD from Wayne State University and his MPH in Epidemiology from the University of Michigan. He completed his residency in Internal Medicine at the University of Michigan and trained as an Epidemic Intelligence Service Officer at the U.S. Centers for Disease Control and Prevention (CDC). Following his EIS training, Dr. Kilgore served as a Medical Epidemiologist in the National Immunization Program at the CDC and as a Commissioned Officer in the U.S. Public Health Service.
His research focuses on vaccine-preventable diseases, infectious disease epidemiology, and antimicrobial resistance. Dr. Kilgore has extensive experience conducting clinical trials and epidemiological studies in the U.S. and internationally. He has served as Principal Investigator (PI), Co-PI, and Co-Investigator on numerous NIH, CDC, and industry-sponsored research projects, including recent COVID-19 vaccine trials. A significant portion of his work is dedicated to addressing health disparities related to infectious diseases in Detroit and other communities across Michigan, the United States, and abroad.
At Wayne State, Dr. Kilgore serves as course director for three key courses: "Foundations in Global Health," which introduces students to critical issues in global health programs and interventions; "Vaccines in Clinical and Public Health Practice," focusing on principles of vaccines and immunizations for various populations; and "Public Health and Population Based Care," which explores population health relevant to practicing pharmacists and public health workers. Through these courses, he prepares students to address both local and global health challenges. Dr. Kilgore is also actively involved in mentoring pharmacy students, residents, and junior faculty. He serves on several university and national committees related to research and public health.
As an expert in infectious diseases and vaccines, Dr. Kilgore is frequently sought out by media outlets to provide commentary on public health issues. He has been a regular guest on local radio programs discussing COVID-19 and other infectious disease topics.
Dr. Kilgore is a Fellow of the American College of Physicians and is board certified in Internal Medicine. He has published over 100 peer-reviewed articles and book chapters throughout his career. His work in public health, both domestically and internationally, continues to inform his research and teaching, preparing the next generation of healthcare professionals to address complex health challenges on a global scale.
Department
Pharmacy Practice
Appointments
2023--present - Professor, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI
Degrees and Certifications
Degrees
- 1991 - Doctor of Medicine, Wayne State University, School of Medicine, Detroit, MI
- 1987 - Masters of Public Health in Epidemiology, University of Michigan School of Public Health, Ann Arbor, MI
- 1985 - Bachelor of Science in Pyschobiology, University of Michigan, College of Literature, Science and the Arts, Ann Arbor, MI
Certifications
- 2012 - National Board of Public Health Examiners
- 2022 - American Board of Internal Medicine
Positions and Employment
- 2023 to present - Professor, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI
- 2011-2023 - Associate Professor, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI
- 2006-2011 - Senior Scientist, Translational Research Division, International Vaccine Institute, Seoul, South Korea
- 1999-2005 - Research Scientist, Translational Research Division, International Vaccine Institute, Seoul, South Korea
- 1997-1999 - Staff Physician, Primary Care Section, Department of Internal Medicine, Department of Veterans Affairs Medical Center, Atlanta, GA
- 1996-1999, Medical Epidemiologist, Public Health Service, Commissioned Corps. Infant Immunization Activity, Child Vaccine Preventable Diseases Branch, National Immunization Program, Centers for Disease Control and Prevention, Atlanta, GA.
Awards and Honors
- 2018 - Fellowship, American College of Physicians
- 2017 - Excellence in Research Award, Eugene Applebaum College of Pharmacy and Health Sciences
- 2009 - Long-term Service Award, International Vaccine Institute, Seoul, Korea
Professional Memberships
- International Society for Vaccines
- American Telemedicine Association
- American Association of Colleges of Pharmacy
- American College of Epidemiology
- American College of Clinical Pharmacy
- American College of Physicians
- American Public Health Association
- American Society of Microbiology
- Infectious Disease Society of America
- Society of Epidemiologic Research
- Society for Clinical Trials
- Society for General Internal Medicine
Primary Research Interest
- The overarching vision of our research program is the reduction of disease burden associated with bacterial and viral infections among infants, children and adults. Our research program focuses on the study of infections using innovative, multi-disciplinary tools that enable more rapid disease diagnosis as well as more accurate ascertainment of the disease burden due to specific infectious pathogens. Our research integrates the application of tools across a wide range of disciplines in order to accurately describe disease burden by age, race/ethnicity, geography and environment. We conduct our research in close cooperation with community partners, non-governmental stakeholders, faith-based organizations, public health experts, and other technical experts with the goal of supporting the development of health programs and policies that improve individual patient outcomes and safety as well as reduce health disparities in the general population. Based on empiric research findings, we conduct rigorously-designed, evidence-based evaluation of interventions to achieve sustainable health gains particularly among underserved populations.
Recent Publications
Chapters Co-Authored
- Paul E. Kilgore and Tom Coenye. Chapter 47: Bordetella and Related Genera in Manual of Clinical Microbiology, 13th Edition. Editors: Karen C. Carroll, Michael A. Pfaller, Marie Louise Landry, Alexander J. McAdam, Robin Patel, Sandra S. Richter, David W. Warnock. American Society of Microbiology, Washington, D.C. 2023.
- Paul E. Kilgore and Tom Coenye. Chapter 47: Bordetella and Related Genera in Manual of Clinical Microbiology, 12th Edition. Editors: Karen C. Carroll, Michael A. Pfaller, Marie Louise Landry, Alexander J. McAdam, Robin Patel, Sandra S. Richter, David W. Warnock. American Society of Microbiology, Washington, D.C. 2019.
Refereed Journals
Please see complete updated list at: https://www.ncbi.nlm.nih.gov/myncbi/paul.kilgore.1/bibliography/public/
(please note that some publications are listed in PubMed and other databases with author name as "Kilgore PE" or "Kilgore P").
- Kanamori D, Sakai J, Iijima T, Oono Y, Malla B, Haramoto E, Hayakawa S, Komine-Aizawa S, Maesaki S, Vorup-Jensen T, Kilgore PE, Kohase H, Hoshino T, Seki M. SARS-CoV-2 detection in pediatric dental clinic wastewater reflects the number of local COVID-19 cases in children under 10 years old. Sci Rep. 2024 May 28;14(1):12187.
- Dhar S, Jinadatha C, Kilgore PE, Henig O, Divine GW, Todter EN, Coppin JD, Carter MJ, Chopra T, Egbert S, Carling PC, Kaye KS. Lowering the Acquisition of Multi-drug Resistant Organism (MDROs) with Pulsed-xenon (LAMP) Study: a cluster randomized controlled, double-blinded, interventional crossover trial. Clin Infect Dis. 2024 May 14;. doi: 10.1093/cid/ciae240
- Fisher LH, Kee JJ, Liu A, Espinosa CM, Randhawa AK, Ludwig J, Magaret CA, Robinson ST, Gilbert PB, Hyrien O, Kublin JG, Rouphael N, Falsey AR, Sobieszczyk ME, El Sahly HM, Grinsztejn B, Gray GE, Kotloff KL, Gay CL, Leav B, Hirsch I, Struyf F, Dunkle LM, Neuzil KM, Corey L, Huang Y, Goepfert PA, Walsh SR, Baden LR, Janes H. SARS-CoV-2 Viral Load in the Nasopharynx at Time of First Infection Among Unvaccinated Individuals: A Secondary Cross-Protocol Analysis of 4 Randomized Trials. JAMA Netw Open. 2024 May 1;7(5):e2412835.
- Joshi S, Arshad S, Lindsay A, Heinonen J, Misikir H, Zervos J, Prentiss T, Verkler J, Numi M, Czander B, David RE, Mossing M, Kilgore PE, Rehman N, Zervos M. Control of SARS-CoV-2 infection in skilled nursing facilities in Detroit, Michigan: a model for emerging infectious diseases. Infect Control Hosp Epidemiol. 2024 Mar 20;:1-3.
- Miran NK, DeLor B, Baker M, Fakhouri J, Metz K, Huskey E, Kilgore P, Fava JP. Vaccine administration by pharmacy technicians: Impact on vaccination volume, pharmacy workflow and job satisfaction. Explor Res Clin Soc Pharm. 2024 Mar;13:100397.
- Rick AM, Laurens MB, Huang Y, Yu C, Martin TCS, Rodriguez CA, Rostad CA, Maboa RM, Baden LR, El Sahly HM, Grinsztejn B, Gray GE, Gay CL, Gilbert PB, Janes HE, Kublin JG, Huang Y, Leav B, Hirsch I, Struyf F, Dunkle LM, Neuzil KM, Corey L, Goepfert PA, Walsh SR, Follmann D, Kotloff KL. Risk of COVID-19 after natural infection or vaccination. EBioMedicine. 2023 Oct;96:104799.
- Theodore DA, Branche AR, Zhang L, Graciaa DS, Choudhary M, Hatlen TJ, Osman R, Babu TM, Robinson ST, Gilbert PB, Follmann D, Janes H, Kublin JG, Baden LR, Goepfert P, Gray GE, Grinsztejn B, Kotloff KL, Gay CL, Leav B, Miller J, Hirsch I, Sadoff J, Dunkle LM, Neuzil KM, Corey L, Falsey AR, El Sahly HM, Sobieszczyk ME, Huang Y. Clinical and Demographic Factors Associated With COVID-19, Severe COVID-19, and SARS-CoV-2 Infection in Adults: A Secondary Cross-Protocol Analysis of 4 Randomized Clinical Trials. JAMA Netw Open. 2023 Jul 3;6(7):e2323349. doi: 10.1001/jamanetworkopen.2023.23349.
- Kim EJ, Lee J, Yoon Y, Lee D, Baek Y, Takano C, Sakai J, Iijima T, Kanamori D, Gardner H, McLaughlin RE, Kilgore PE, Nakamura A, Ogihara T, Hayakawa S, Hoshino T, Kim DW, Seki M. Development of a novel loop-mediated isothermal amplification assay for ß-lactamase gene identification using clinical isolates of Gram-negative bacteria. Front Cell Infect Microbiol. 2023 Jan 12;12:1000445.
- Hardt K, Vandebosch A, Sadoff J, Le Gars M, Truyers C, Lowson D, Van Dromme I, Vingerhoets J, Kamphuis T, Scheper G, Ruiz-Guiñazú J, Faust SN, Spinner CD, Schuitemaker H, Van Hoof J, Douoguih M, Struyf F; ENSEMBLE2 study group. Efficacy, safety, and immunogenicity of a booster regimen of Ad26.COV2.S vaccine against COVID-19 (ENSEMBLE2): results of a randomised, double-blind, placebo-controlled, phase 3 trial. Lancet Infect Dis. 2022 Dec;22(12):1703-1715.
- Sandhu A, Polistico JMF, Meyer MP, Gonzalez G, Kiama K, Lebednick M, Prentiss T, Misikir H, Heinonen J, Zervos J, Kilgore PE, Zervos MJ, Fink LR, Rehman NK, Maples C, Chopra T. Pandemic response gaps: Infection prevention and control lessons learned during coronavirus disease 2019 (COVID-19) outbreaks in skilled nursing facilities in Detroit, Michigan. Infect Control Hosp Epidemiol. 2022 Aug 10:1-5.
- Sobeck J, Smith-Darden J, Gartner D, Kaljee L, Pieper B, Kilgore P, Zervos M. Antibiotic Knowledge, Beliefs, and Behaviors: Testing Competing Hypotheses Using an Urban Community Sample. Health Commun. 2022 Jun;37(7):862-871.
- Iijima T, Ando S, Kanamori D, Kuroda K, Nomura T, Tisi L, Kilgore PE, Percy N, Kohase H, Hayakawa S, Seki M, Hoshino T. Detection of SARS-CoV-2 and the L452R spike mutation using reverse transcription loop-mediated isothermal amplification plus bioluminescent assay in real-time (RT-LAMP-BART). PLoS One. 2022 Mar 21;17(3):e0265748.
- Gilbert PB, Montefiori DC, McDermott AB, Fong Y, Benkeser D, Deng W, Zhou H, Houchens CR, Martins K, Jayashankar L, Castellino F, et al. Immune Assays Team; Moderna, Inc. Team; Coronavirus Vaccine Prevention Network (CoVPN)/Coronavirus Efficacy (COVE) Team; United States Government (USG)/CoVPN Biostatistics Team. Immune correlates analysis of the mRNA1273 COVID-19 vaccine efficacy clinical trial. Science. 2022 Jan 7;375(6576):43-50.
- Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, Goepfert PA, Truyers C, Van Dromme I, Spiessens B, Vingerhoets J, Custers J, Scheper G, Robb ML, Treanor J, Ryser MF, Barouch DH, Swann E, Marovich MA, Neuzil KM, Corey L, Stoddard J, Hardt K, Ruiz-Guiñazú J, Le Gars M, Schuitemaker H, Van Hoof J, Struyf F, Douoguih M; ENSEMBLE Study Group (Paul Kilgore Member of ENSEMBLE Study Group). Final Analysis of Efficacy and Safety of Single-Dose Ad26.COV2.S. N Engl J Med. 2022 Mar 3;386(9):847-860.
- Takano C, Seki M, Kim DW, Kilgore PE, Fuwa K, Takahashi K, Inazaki T, Hayakawa S. Corrigendum: Molecular Serotype-Specific Identification of Nontype b Haemophilus influenzae by Loop-Mediated Isothermal Amplification. Front Microbiol. 2022 Mar 14;13:870651. doi: 10.3389/fmicb.2022.870651.
- McKinnon JE, Wang DD, Zervos M, Saval M, Marshall-Nightengale L, Kilgore P, et al. Safety and tolerability of hydroxychloroquine in health care workers and first responders for the prevention of COVID-19: WHIP COVID-19 Study. Int J Infect Dis. 2021 Dec 23;116:167-173.
- Chen Y, Zhao YL, Hao ZY, Zhang XJ, Ma JC, Zhang ZY, Zhang YH, Zhao G, Qiu C, Kilgore PE, Wang SM, Wang XY. Long-term persistence of antiHAV antibody conferred by a single dose of live-attenuated hepatitis A vaccine: Results from 17-year follow-up. J Viral Hepat. 2021 Dec;28(12):1751-1755.
- El Sahly HM, Baden LR, Essink B, Doblecki-Lewis S, Martin JM, Anderson EJ, Campbell TB, Clark J, Jackson LA, Fichtenbaum CJ, Zervos M, et al; COVE Study Group (Paul Kilgore Member of COVE Study Group). Efficacy of the mRNA-1273 SARS-CoV-2 Vaccine at Completion of Blinded Phase. N Engl J Med. 2021 Nov 4;385(19):1774-1785.
- Sadoff J, Gray G, Vandebosch A, Cárdenas V, Shukarev G, Grinsztejn B, Goepfert PA, Truyers C, Fennema H, Spiessens B, Offergeld K, Scheper G, Taylor KL, Robb ML, Treanor J, Barouch DH, Stoddard J, Ryser MF, Marovich MA, Neuzil KM, Corey L, Cauwenberghs N, Tanner T, Hardt K, Ruiz-Guiñazú J, Le Gars M, Schuitemaker H, Van Hoof J, Struyf F, Douoguih M; ENSEMBLE Study Group (Paul Kilgore Member of ENSEMBLE Study Group). Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19. N Engl J Med. 2021 Jun 10;384(23):2187-2201.
- Lee J, Yoon Y, Kim EJ, Lee D, Baek Y, Takano C, Chang B, Iijima T, Kilgore PE, Hayakawa S, Hoshino T, Kim DW, Seki M. 23-valent polysaccharide vaccine (PPSV23)-targeted serotype-specific identification of Streptococcus pneumoniae using the loop-mediated isothermal amplification (LAMP) method. PLoS One. 2021 Feb 16;16(2):e0246699.
- Baden LR, El Sahly HM, Essink B, Kotloff K, Frey S, Novak R, Diemert D, Spector SA, Rouphael N, Creech CB, McGettigan J, Khetan S, Segall N, Solis J, Brosz A, Fierro C, Schwartz H, Neuzil K, Corey L, Gilbert P, Janes H, Follmann D, Marovich M, Mascola J, Polakowski L, Ledgerwood J, Graham BS, Bennett H, Pajon R, Knightly C, Leav B, Deng W, Zhou H, Han S, Ivarsson M, Miller J, Zaks T; COVE Study Group (listed in Supplemental Materials). Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine. N Engl J Med. 2021 Feb 4;384(5):403-416.
- Lucien MAB, Canarie MF, Kilgore PE, Jean-Denis G, Fénélon N, Pierre M, Cerpa M, Joseph GA, Maki G, Zervos MJ, Dely P, Boncy J, Sati H, Rio AD, Ramon-Pardo P. Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings. Int J Infect Dis. 2021 Jan 9;104:250254.
- Zervos M, Arshad S, Kilgore P, Chaudhry ZS, Jacobsen G, Wang DD, Huitsing K, Brar I, Alangaden GJ, Ramesh MS, McKinnon JE, O'Neill W. A sound approach: Hydroxychloroquine reduces mortality in severe COVID-19. Int J Infect Dis. 2020 Oct;99:138-139.
- Arshad S, Kilgore P, Chaudhry ZS, Jacobsen G, Wang DD, Huitsing K, Brar I, Alangaden GJ, Ramesh MS, McKinnon JE, O'Neill W, Zervos M; Henry Ford COVID-19 Task Force. Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19. Int J Infect Dis. 2020 Aug;97:396-403.
- Mudali G, Kilgore PE, Salim A, McElmurry SP, Zervos M. Trends in Legionnaires' Disease-Associated Hospitalizations, United States, 2006-2010. Open Forum Infect Dis. 2020 Jul 17;7(8):ofaa296.
- Sobeck J, Smith-Darden J, Hicks M, Kernsmith P, Kilgore PE, TreemoreSpears L, McElmurry S. Stress, Coping, Resilience and Trust during the Flint Water Crisis. Behav Med. 2020 Jul-Sep;46(3-4):202-216.
- Sanchez GV, Biedron C, Fink LR, Hatfield KM, Polistico JMF, Meyer MP, Noe RS, Copen CE, Lyons AK, Gonzalez G, Kiama K, Lebednick M, Czander BK, Agbonze A, Surma AR, Sandhu A, Mika VH, Prentiss T, Zervos J, Dalal DA, Vasquez AM, Reddy SC, Jernigan J, Kilgore PE, Zervos MJ, Chopra T, Bezold CP, Rehman NK. Initial and Repeated Point Prevalence Surveys to Inform SARS-CoV-2 Infection Prevention in 26 Skilled Nursing Facilities - Detroit, Michigan, March-May 2020. MMWR Morb Mortal Wkly Rep. 2020 Jul 10;69(27):882-886.
- Henig O, Pogue JM, Martin E, Hayat U, Ja'ara M, Kilgore PE, Cha R, Dhar S, Kaye KS. The Impact of Multidrug-Resistant Organisms on Outcomes in Patients With Diabetic Foot Infections. Open Forum Infect Dis. 2020 May 6;7(5):ofaa161.
- Wagner, JL, Carreno, JJ, Kenney, RM, Kilgore, PE, Davis, SL. Antimicrobial Stewardship Metrics that Matter. Infect Dis Clin Pract. 2020 Mar;28(2):89-93.
- Takano C, Kuramochi Y, Seki M, Kim DW, Omagari D, Sasano M, Chang B, Ohnishi M, Kim EJ, Fuwa K, Kilgore PE, Hoshino T, Hayakawa S. Molecular serotype-specific identification of Streptococcus pneumoniae using loop-mediated isothermal amplification. Sci Rep. 2019 Dec 27;9(1):19823.
Research website
https://orcid.org/0000-0003-3214-4482
DO NOT EDIT: Experts guide blurb
Paul Kilgore leads a research program in vaccines, infectious disease epidemiology and health disparities that aims to reduce the disease burden associated with bacterial and viral infections among infants, children and adults, particularly among underserved populations. He is also actively engaged in global health research overseas in Asia and other regions, developing novel interventions to improve prevention and control of globally important infectious diseases. He has also been active in research and teaching at the intersection of public health and environmental health in Michigan and other locations.