| projects |
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| Alternate Splicing and the Estrogen Receptor in Pregnancy (ongoing) |
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| Fetal Maternal Signaling (ongoing) |
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| Faculty Profile |
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Office Address
C.S. Mott Center
275 E. Hancock
Phone
313-577-2153
Position Title
Assistant Professor-Obstetrics and Gynecology
Narrative Bio
I am not accepting any new students at this time.
Publications
For a complete list of publications, please visit Suria PubMed
Post Graduate Training
1997-2000 Postdoctoral Fellow, University of Texas Southwestern Medical Center, Department of Internal Medicine
2000-2004 Postdoctoral Fellow, University of texas Southwestern Medical Center, Department of Biochemistry
- 1996 Graduate student representative of the fitness association, Center of Marine Biotechnology, MD
- 1995 Graduate student representative of the parking and safety committee, Center of Marine Biotechnology, MD
- 1993-95 Maryland Sea Grant Trainee
- 1993 Winner of poster award at the Annual Biotechnology Symposium of the Maryland Biotechnology Institute, Center for Advanced Research in Biotechnology, Shady Grove, MD
Education
1997 - Ph.D. in Marine Estuarine, Environmental Science, Unviersity of Maryland
Suffix
Ph.D.
Research Description
Dr. Jeyasuria (Suria) Pancharatnam joined the Wayne State University’s Department of Obstetrics and Gynecology from the University of Pittsburgh’s Magee-Women’s Research Institute. He was recruited by the WSU Perinatal Initiative in support of the Perinatology Research Branch. He received his PhD in Marine Estuarine Environmental Sciences at the University of Maryland and completed his postdoctoral studies at the University of Texas Southwestern Medical Center in the laboratory of Dr. Keith L. Parker. Dr Jeyasuria has ongoing research support by the NIH and March of Dimes. His research utilizes molecular and transgenic approaches to target his investigational interests in the field of reproductive endocrinology and physiology. A common thread in his projects is nuclear receptor function, recently focusing on the characterization and functional analysis of alternate ERα isoforms, which play a critical role in regulating estrogen (E2) responsiveness in a spatial and gestationally regulated manner in the myometrial compartment of the pregnant uterus.
My second research focus has been dedicated to understanding maternal fetal signalling with respect to the phenomena of imprinting and fetal growth. To study the fetal component of this process, I have created a strategy to ablate specific genes in all fetuses while the maternal genome remains somatically wild type. These studies will allow us to determine different gene actions that are involved in the interactions between the fetus and mother during gestation.
My final area of interest is in sex determination and differentiation. These projects have a common thread in that I use transgenic approaches to understand gene function in the developing gonad. To date have made an androgen receptor rescue mouse in order to understand the functional relevance of mutations in the androgen receptor. Following this line of investigation I have also created tissue specific knockouts of the NR5A1 (a nuclear receptor) in the Sertoli cell and created a mouse model to understand the germ cell (i.e. the precursors of oocytes and sperm) development.
Web Site: http://jeyasuria.wayne.edu
My second research focus has been dedicated to understanding maternal fetal signalling with respect to the phenomena of imprinting and fetal growth. To study the fetal component of this process, I have created a strategy to ablate specific genes in all fetuses while the maternal genome remains somatically wild type. These studies will allow us to determine different gene actions that are involved in the interactions between the fetus and mother during gestation.
My final area of interest is in sex determination and differentiation. These projects have a common thread in that I use transgenic approaches to understand gene function in the developing gonad. To date have made an androgen receptor rescue mouse in order to understand the functional relevance of mutations in the androgen receptor. Following this line of investigation I have also created tissue specific knockouts of the NR5A1 (a nuclear receptor) in the Sertoli cell and created a mouse model to understand the germ cell (i.e. the precursors of oocytes and sperm) development.
Web Site: http://jeyasuria.wayne.edu