Pramod Khosla

Faculty Profile

Associate Professor
aa0987@wayne.edu

Department

Nutrition and Food Science

Phone

313 577 0448

Fax

313 577 8616

Office

 Room 3002 Science Hall

Biography

Dr Khosla has been working on diet and lipoprotein metabolism for almost thirty years. After obtaining his BSc and MSc from Newcastle University in the UK and PhD from the University of Western Ontario in Canada, he did post-doctoral research at Brandeis University in the USA. Dr Khosla is the author of some eighty plus articles including original research, book chapters, reviews and commentaries. He has been involved in dietary-fat related research/education for several years and given over a hundred invited guest lectures and seminars in >30 countries. He has supervised 35 graduate students (PhD, MS and MA) and taught over eighty classes (11 different courses). Over the last few years, Dr Khosla’s laboratory has carried out studies in dialysis patients to look at the effects of various supplements (omega 3 fatty acids,  tocotrienols) on markers of inflammation, oxidative stress and blood lipids. He is currently the lead investigator on a multi-centered clinical trial involving various dialysis units in Michigan (Henry Ford, Great Lakes Dialysis, Davita) as well as Universiti Kebangsaan Malaysia (UKM)  and Universiti Putra Malaysia (UPM), evaluating the effects of tocotrienol supplementation on lipid, inflammatory and oxidative stress markers. He is also the lead investigator in a collaborative study looking at various aspects of diet on protein energy wasting (PEW) in dialysis patients. This work, in addition to UKM and UPM, involves collaborative centers in the Bangladesh, Saudi Arabia and India

Selected Publications

Khor, B-H., Sahathevan, S., Ali, M.S.M., Narayanan, S. S., Chinna, K., Gafor, A.H.A, Goh, B-L., Ghazali, A., Morad, Z., Daud, Z.A.M., Khosla, P., Sundram, K. and Karupaiah, T. (2018)  Circulating Fatty Acid Status as an Indicator of Dietary fat Intakes in Hemodialysis Patients. Nutrition, 63-64, 14-21

Tallman, D., Sahathevan, S., Karupaiah, T. and Khosla, P. (2018) Egg Intake in Chronic Kidney Disease. Nutrients, 10, 1945; doi.org/10.3390/nu10121945

Khor, B-H., Narayanan, S. S., Chinna, K., Gafor, A.H.A, Daud, Z.A.M., Khosla, P., Sundram, K. and Karupaiah, T. (2018) Blood Fatty Acid Status and Clinical outcomes in Dialysis Patients. Nutrients, 10: 1353; doi: 10.3390/nu/10101353 562

Khor, B-H., Narayanan, S. S., Sahathevan, S., Gafor, A.H.A, Daud, Z.A.M., Khosla, P., Sabatino, A., Fiaccadori, E., Chinna, K. and Karupaiah, T. (2018) Efficacy of Nutritional Interventions on Inflammatory Markers in Hemodialysis Patients: A Systematic Review and Limited Meta-Analysis. Nutrients, 10: 397-407

Courses taught

Previously I have taught the following courses in the Department

NFS 2030 Nutrition and Health (10 semesters); NFS 3230 Human Nutrition (6 semesters); NFS 5230 Human Nutrition and Metabolism (28 semesters); NFS 6280 Physiology and Nutrition - for High School Science Teachers (3 semesters); NFS 6850 Controversial Issues (5 semesters); NFS 7140 Advanced Lab techniques (1 semester), NFS 7890 Advanced Workshop on Lipid Metabolism (1 semester)

Research Description

We are interested in the role of specific dietary components on cholesterol and lipoprotein metabolism. Current projects are focused on 1) dietary interventions to decrease oxidative stress and inflammation in patients undergoing hemodialysis 2) the effects of dietary fatty acids on plasma lipoprotein metabolism 3) the nutritional properties of palm oil and its constituents (carotenoids, tocotrienols)

Affiliated Departments