Lipid Droplets in Health and Disease

This is an ongoing project.

Faculty Researcher: Emilio Mottillo

Contact Details

Emilio Mottillo
emottil1@hfhs.org
313-432-7251

Description

The project investigates how cells store and release lipids in organelles called lipid droplets. Importantly, the process by which cells store lipids goes wrong in various diseases. Our lab investigates the protein interactions that occur on the surface of lipid droplets and how the disruption of these interactions can lead to cardiometabolic diseases such as fatty liver disease, cardiovascular disease and kidney disease.

Students will learn the following:
-cell culture
-crispr-Cas9 Genome editing
-western blotting
-fluorescent microscopy
-Data analysis and interpretation
-Data presentation and communication
-how to think independently

Qualifications

Basic understanding and interest in cell biology and physiology.
Previous experience in cell biology is suggested.
Interest in cell biology and metabolism.
Hard working, curious and inquisitive!

Project Timeline

Students will need to commit for at least 2 full semesters (including summer)

Duties

Spend 8-10 hours per week on project-related activities in the lab
Meet weekly in lab meetings with lab and Professor
Communication and presentation of data
Keep detailed notes of project-related activities
Work as part of a team to answer important research questions
Have fun!

Last Updated

February 5, 2024