Office Address
C.S. Mott Center
275 E. Hancock
Position Title
Charlotte B. Failing Professor of Fetal Therapy & Diagnosis Department of Ob/Gyn
Joint Appointments
Center for Molecular Medicine and Genetics
Narrative Bio
Dr. Krawetz will consider new MS and PhD students for the 2020-21 academic year.
Laboratory Web Site
http://compbio.med.wayne.edu/
Publications
For a complete list of publications, please visit Krawetz PubMed
Research Description
Over the last two decades, his group established that the fitness of the paternal contribution reflects the relative diversity of sperm RNAs that continually respond to the environment. These RNAs may provide an essential component to early paternal genome reprogramming, acting as genetic and epigenetic impactors of the fetal onset of adult disease. They provide a personalized timestamp of the physical and reproductive health of the father, providing the opportunity to develop a personalized blueprint promoting the birth and healthy life of the couple’s children.
Computational and wet-bench positions are immediately available as part of an interdisciplinary research team using advanced high-throughput and analysis strategies and Computational technologies to determine how RNA regulates gene expression in early development. The Krawetz group using a systems approach to determine how the delivery of sperm RNAs are essential to early development and their perturbation modulates the Fetal Origins of Adult Disease.