| projects |
|
| Clinical Trial in Healthy Volunteers (closed) |
|
| Faculty Profile |
|
Suffix
Pharm.D.
Office Location
4154
Phone
313-577-3132
Department
Pharmacy Practice
Degrees and Certifications
Degrees
- 2011-2014 - Post-Doctoral Research Fellow, Pharmacogenomics Lab, University of Michigan College of Pharmacy, Department of Clinical, Social and Administrative Sciences
- 2011 - University of Michigan, College of Pharmacy, Ann Arbor, Doctorate of Pharmacy with Distinction
- 2005-2007 - University of Michigan, College of LS&A, Pre-Pharmacy/Biochemistry
- 2004-2005 - University of California at Santa Cruz, Pre-Pharmacy/Biochemistry
Certifications
- 2021 - Certificate in Applied Biostatsitics, Harvard University Catalyst
- 2019 - Certificate in Clinical Research Conduct & Management, University of California Berkeley Ext.
- 2014 - American College of Clinical Pharmacy Focused Investigator Training Program
- 2013 - MI Regional Comprehensive Metabolomics Resource Cores Summer Metabolomics Workshop
- 2012 - Institute of General Medical Sciences 2nd Annual Short Course on Statistical, Genetics & Genomics
- 2012 - Statistical Analysis with R Workshop, Michigan Center for Statistical Consultation and Research
Positions and Employment
- 2020-present - Associate Professor of Pharmacy Practice - Tenured, Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences
- 2014-2020 - Assistant Professor of Pharmacy Practice - Tenure Track, Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences
- 2011-2014 - Pharmacist at Schmidt and Sons Pharmacy (Tecumseh, MI)
- 2009 - Research Assistant with the Highland Park Project under the Ginsberg Research Grant, University of Michigan College of Pharmacy, Department of Clinical, Social and Administrative Sciences
- 2005-2006 - Research Assistant in the Molecular and Behavioral Neuroscience Institute Watson/Akil Lab, University of Michigan School of Medicine
Awards and Honors
- 2024 - Journal of Neuroscience Research top 10 most-cited papers published (J Neurosci Res. 2022 publication)
- 2024 - The Gary A. Dudley Memorial Paper Scientific Manuscript Excellence Honor (J Strength Cond Res 2024 publication)
- 2020 - American College of Clinical Pharmacy New Investigator 2020 Award
- 2019 - Original Research Award Winner for College of Psychiatric and Neurologic Pharmacist Association
- 2017 - American College of Clinical Pharmacy Poster Accepted for CE presentation
- 2016 - Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences College Research Day Poster Award (Mentor to Brittany Lines)
- 2016 - Undergraduate Research Opportunity Program Grant (Mentor to Nadeen Mansour)
- 2016 - American College of Clinical Pharmacy New Investigator Award Nomination
- 2015 - College of Psychiatric and Neurologic Pharmacist Original Research Award
- 2014 - American Society of Clinical Psychopharmacology (ACSP) Annual Meeting - New Investigator Award recipient
- 2014 - Poster Award Finalist at the Schizophrenia International Research Society 2014 Meeting
- 2012 - Travel Fellowship Award for National Institute of General Medical Sciences 2nd Annual Short Course on Statistical Genetics and Genomics
- 2011 - Doctor of Pharmacy: Community Service Award
- 2009-2010 - Gertrude and George Huebner Scholarship
- 2010 - R.A. Deno Award for Significant Improvement in Scholarship
Professional Memberships
- 2014-present - American Association of Colleges of Pharmacy
- 2011-present - American College of Clinical Pharmacy
- 2009-present - College of Psychiatric and Neurologic Pharmacists
Primary Research Interest
Active
- 2024 American Association of Colleges of Pharmacy New Investigator Grant – Mentor on grant (PI: Adeosun Samuel): Amount: $10,000
- 2024 Commission on Dietetic Registration Emerging Researcher Grant. Academy of Nutrition and Dietetics Foundation – Co-Investigator on grant (PI: Maria Dingh) Amount: $10,000
- 2023 District IV National Association Boards of Pharmacy/American Association of Colleges of Pharmacy Grant Award to Pharmacy Students – Co-mentor on grant (PI: Shannon Habba). Amount: $4,500
Completed
- American Association of Colleges of Pharmacy Science of Teaching and Learning Grant.“ Effects of Hands-On Personalized Genetic Testing in Pharmacogenetics Education” Role: Primary Investigator (5%) Amount: $4500
- NIH K23 Patient-Oriented Career Development Award. Funding IC: NIDDK - K23DK118199 “Acutely Induced Insulin Resistance by Antipsychotic Medication in Healthy Volunteers: Impact of Skeletal Muscle Epigenomic and Proteomic Mechanisms” Role: PI (75%) Amount: $675,168
- NIH K23 Retention Supplement. Funding IC: NIDDK - K23DK118199S1. Supplement to “Acutely Induced Insulin Resistance by Antipsychotic Medication in Healthy Volunteers: Impact of Skeletal Muscle Epigenomic and Proteomic Mechanisms” Role: PI (75%) Amount: $53,887
- National Institutes of Health Loan Repayment Program for Extramural Clinical Research. Funding IC: National Institute of Diabetes Digestive and Kidney Diseases (NIDDK) “Mechanisms of antipsychotic-induced insulin resistance in the skeletal muscle." NIH - L30 DK110823 Role: Primary Investigator. Amount: $112,422.99 (renewed in 2018 and 2019 and 2020)
Recent Publications
Chapters Published
- Howlett BH, Kassa M, Burghardt KJ*. 1st ed. Machado-Vieira R and Soares JC (Editors). Elsevier (New York); 2022. Biomarkers in Bipolar Disorders. Chapter 15. DNA Methylation in Bipolar Disorder. Pgs. 267-286.
Refereed Journals
- Burghardt KJ*, Burghardt PR, Howlett BH, Dass SE, Zahn B, Imam A, Mallisho A, Msallaty Z, Seyoum B, Yi Z. Alterations in Skeletal Muscle Insulin Signaling DNA Methylation. A Pilot Randomized Controlled Trial of Olanzapine in Healthy Volunteers. Biomedicines 2024, 12, 1057.
- Arroum T, Hish GA, Burghardt KJ, McCully JD, Hüttemann M**, Malek MH**. (**Designates co-senior authors). Mitochondrial Transplantation’s Role in Rodent Skeletal Muscle Bioenergetics: Recharging the Engine of Aging. Biomolecules 2024, xxxxxx
- Stewart B*, Habba S, Burghardt KJ. Michigan Pharmacists Association. The Official Journal of the Michigan Pharmacists Association. 2024. Apr 14; 62(2): 16-17
- Arroum, T., G. A. Hish, K. J. Burghardt, M. Ghaloush, B. Bazzi, A. Mrech, P. T. Morse, S. L. Britton, L. G. Koch, J. D. McCully, M. Hüttemann**, M. H. Malek**. (**Designates co-senior authors). Mitochondria transplantation: rescuing innate muscle bioenergetic impairment in a model of aging and exercise intolerance. J Strength Cond Res, x(x): xxxx-xxxx, in press (paper given award - see award section).
- Burghardt KJ*, Kajy M, Ward KM, Burghardt PR. Metabolomics, Lipidomics, and Antipsychotics: A Systematic Review. Biomedicines 2023, 11(12), 3295.
- Rowbal T, Kajy M, Burghardt KJ*. Epigenome-Wide Studies of Antipsychotics: A Systematic Review and Pathway Meta-Analysis. Epigenomics. 2023 Oct;15(20):1085-1094.
Burghardt KJ*, Mando M, Seyoum B, Yi Z, Burghardt PR. The Effect of Antipsychotic Treatment on Hormonal, Inflammatory and Metabolic Biomarkers in Healthy Volunteers; A Systematic Review and Meta-Analysis. Accepted. In Press.
- Burghardt KJ*, Calme G, Caruso M, Howlett BH, Sanders E, Zhang X, Msallaty Z, Mallisho A, Seyoum B, Qi YA, Yi Z. Profiling the Skeletal Muscle Proteome in Patients on Atypical Antipsychotics and Mood Stabilizers. Brain Sciences (MDPI). 2022; 12(2):259.
- Zabik NL, Iadipaolo AS, Marusak HA, Peters C, Burghardt KJ, Rabinak CA*. A Common Genetic Variant in Fatty Acid Amide Hydrolase is Linked to Alterations in Fear Extinction Neural Circuitry in a Racially Diverse, Non-Clinical Sample of Adults. Journal of Neuroscience Research. 2022 Mar;100(3):744-761.
- Mestareehi A, Zhang X, Seyoum B, Msallaty Z, Abdullah Mallisho A, Burghardt KJ, Kowluru A, Yi Z*. Metformin Increases Protein Phosphatase 2A Activity In Primary Human Skeletal Muscle Cells Derived from Lean Healthy Participants. Journal of Diabetes Research (Hindawi). 2021 Jul 28;2021:9979234.
- Ward KM*, Burghardt KJ, Kraal AZ, Jaeger A, Yeomans L, Mchugh C, Karnovsky A, Stringer KA, Ellingrod VL. Genetic and Metabolite Variability in One-Carbon Metabolism Applied to an Insulin Resistance Model in Patients with Schizophrenia Receiving Atypical Antipsychotics. Frontiers Neuroscience. 2021 May 25;12:623143.
- Burghardt KJ*, Ward KM, Howlett BH, Burghardt PR. Personal Genotyping and Student Outcomes in Genetic and Pharmacogenetic Teaching; A Systematic Review and Meta-Analysis. Pharmacogenomics (Futures Medicine). 2021 May;22(7):423-433
- Ward KM*, Taubman DS, Pasternak AL, Burghardt KJ, Ellingrod VL, Parikh SV. Teaching Psychiatric Pharmacogenomics Effectively: Evaluation of a Novel Interprofessional Online Course. Journal of the American College of Clinical Pharmacy. February 2021. 4(2). 176-183.
- Burghardt KJ*, Howlett BH, Khoury A., Fern SM, Burghardt PR. Bibliometric data based on the Pharm.D. and Ph.D. degree in United States research-intensive colleges of pharmacy. International Journal of Pharmacy Practice. 2021 Feb 10;29(1):78-83.
- Burghardt KJ*, Howlett BH, Khoury A., Fern SM, Burghardt PR. Three Commonly Utilized Scholarly Databases and a Social Network Site Provide Different, but Related, Metrics of Pharmacy Faculty Publication. Publications 2020, 8(2), 18.
- Burghardt KJ*, Khoury A, Msallaty Z, Yi Z, Seyoum B. Antipsychotic Medications and DNA Methylation in Schizophrenia and Bipolar Disorder: A Systematic Review. Pharmacotherapy. Accepted 1/24/2020.
- Burghardt KJ*, Howlett BH, Fern SM, Burghardt PR. A Bibliometric Analysis of the Top 50 NIH-Funded Colleges of Pharmacy Using Two Databases. Research in Social and Administrative Pharmacy. 2019 Oct 9. pii: S1551-7411(19)30677-1.
- Burghardt KJ*, Howlett BH, Sanders E, Dass SE, Msallaty Z, Mallisho A, Seyoum B, Yi Z. Skeletal Muscle DNA Methylation Modifications and Psychopharmacologic Treatment in Bipolar Disorder. European Neuropsychopharmacology. 2019 Oct 18. pii: S0924-977X(19)31700-6.
- Kraal, AZ*, Moll AC, Arvanitis NR, Ward KM, Dougherty RJ, Grove TB, Burghardt KJ, Ellingrod VL. Metabolic Syndrome is Negatively Associated with Cognition among Endothelial Nitric Oxide Synthase (eNOS)-786C carriers in Schizophrenia-Spectrum Disorders. Journal of Psychiatric Research. 2019 Oct;117:142-147.
Non-Refereed Journals
- Stewart B*, Habba S, Burghardt KJ. Michigan Pharmacists Association. The Official Journal of the Michigan Pharmacists Association. 2024. Apr 14; 62(2): 16-17
Research website
https://orcid.org/0000-0003-2319-5149
DO NOT EDIT: Experts guide blurb
Kyle Burghardt has done extensive research on insulin resistance.
Research Description
Ongoing
NIH K23 Patient-Oriented Career Development Award
Funding IC: NIDDK - K23DK118199
“Acutely Induced Insulin Resistance by Antipsychotic Medication in Healthy Volunteers: Impact of Skeletal Muscle Epigenomic and Proteomic Mechanisms”
Role: PI (75%)
American Association of Colleges of Pharmacy
Science of Teaching and Learning Grant
“Effects of Hands-On Personalized Genetic Testing in Pharmacogenetics Education”
Role: Primary Investigator (5%)
Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences Faculty Research Award Program (FRAP) Collaborative Grant
“The Role of Transposable Elements in Neurotoxic Effects of Chronic Methamphetamine”
Role: Co-Primary Investigator
National Institutes of Health Loan Repayment Program for Extramural Clinical Research
Funding IC: National Institute of Diabetes Digestive and Kidney Diseases (NIDDK)
“Mechanisms of antipsychotic-induced insulin resistance in the skeletal muscle”
NIH - L30 DK110823
Role: Primary Investigator
Completed
Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences Faculty Research Award Program (FRAP) Collaborative Grant
“Insulin Resistance Induced by Antipsychotic Medication in the Absence of Obesity: Impact of Skeletal Muscle Protein Kinase-based Mechanisms”
Role: Primary Investigator (15%)
Brain & Behavior Research Foundation
NARSAD Young Investigator Grant
“Effects of FAAH Genotype on Fear-Related Brain Activation during Fear Extinction”
Role: Co-Investigator (5%)
Michigan Diabetes Research Center (MDRC)
P30 Pilot/Feasibility Grant
“Insulin Resistance Induced by Antipsychotic Medication in the Absence of Weight Gain: Impact of Skeletal Muscle Epigenetic and Protein Mechanisms”
NIH Grant 2P30-DK020572
Role: Primary Investigator
American College of Clinical Pharmacy
Futures Research Junior Investigator Grant
“Insulin Resistance Induced by Antipsychotic Medication in the Absence of Obesity: Impact of DNA Methylation and Lipids in the Skeletal Muscle”
Role: Primary Investigator
Wayne State University Office of the Vice President for Research.
Research Mentors Program for New Faculty
PIs: Yi and Burghardt
NIH: NIMH
Sex as a Biological Variable Supplement
“The Role of Sex in the Epigenetics of Antipsychotic-induced Metabolic Syndrome”
PI: Ellingrod
NIH R01 MH082784 S1
Role: Co-I.
Facilitate all sample preparation, analyses and data presentation. Publish results.
Recent Publications
NCBI
ORCiD
Burghardt KJ*, Howlett BH, Khoury A., Fern SM, Burghardt PR. Three Commonly Utilized Scholarly Databases and a Social Network Site Provide Different, but Related, Metrics of Pharmacy Faculty Publication. Publications 2020, 8(2), 18.
Burghardt KJ*, Khoury A, Msallaty Z, Yi Z, Seyoum B. Antipsychotic Medications and DNA Methylation in Schizophrenia and Bipolar Disorder: A Systematic Review. Pharmacotherapy. Accepted 1/24/2020.
Burghardt KJ*, Howlett BH, Fern SM, Burghardt PR. A Bibliometric Analysis of the Top 50 NIH-Funded Colleges of Pharmacy Using Two Databases. Research in Social and Administrative Pharmacy. 2019 Oct 9. pii: S1551-7411(19)30677-1.
Burghardt KJ*, Howlett BH, Sanders E, Dass SE, Msallaty Z, Mallisho A, Seyoum B, Yi Z. Skeletal Muscle DNA Methylation Modifications and Psychopharmacologic Treatment in Bipolar Disorder. European Neuropsychopharmacology. 2019 Oct 18. pii: S0924-977X(19)31700-6.
Kraal, AZ*, Moll AC, Arvanitis NR, Ward KM, Dougherty RJ, Grove TB, Burghardt KJ, Ellingrod VL. Metabolic Syndrome is Negatively Associated with Cognition among Endothelial Nitric Oxide Synthase (eNOS)-786C carriers in Schizophrenia-Spectrum Disorders. Journal of Psychiatric Research. 2019 Oct;117:142-147.
James R. Bagley, Kyle J. Burghardt, Ryan McManus, Irene S. Tobias, Bradley Howlett, Pablo B. Costa, Jared W. Coburn, Jose A. Arevalo, Moh H. Malek, and Andrew J. Galpin*. Epigenetic Responses To Acute Resistance Exercise In Trained Vs. Sedentary Men. Journal of Strength and Conditioning Research. In Press.
Burghardt KJ, Ward KM, Sanders E, Howlett BH, Seyoum B, Yi Z. Atypical Antipsychotics and the Human Skeletal Muscle Lipidome. Metabolites. 2018 Oct 13;8(4).
Bacon OM, Burghardt DR, Burghardt KJ. Management of pain in a patient taking naltrexone and needing an outpatient procedure. Current Psychiatry. Current Psychiatry. 2018 September;17(9):46-48.
Burghardt KJ, Goodrich JM, Line BN, EllingrodVL. The Influence of Metabolic Syndrome and Sex on the DNA Methylome in Schizophrenia. Int J Genomics. Volume 2018 (2018), Article ID 8076397, 12 pages.
Burghardt KJ, Seyoum B, Dass SE, Sandera E, Mallisho A, Yi Z. Association of Protein Kinase B (AKT) DNA Hypermethylation with Maintenance Atypical Antipsychotic Treatment in Patients with Bipolar Disorder. Pharmacotherapy. 2018 Apr;38(4):428-435.
Burghardt KJ, Seyoum B, Mallisho A, Burghardt PR, Kowluru RA, Yi Z. Atypical antipsychotics, insulin resistance and weight; a meta-analysis of healthy volunteer studies. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Apr 20;83:55-63.
Burghardt KJ, Jaber LA. Haptoglobin Gene Polymorphisms and Diabetes Risk in the Arab-American Population. Submitted to Biomarkers in Medicine. Biomarkers in Medicine. Biomark Med. 2017 Nov;11(11):937-945.
Moszczynska A, Burghardt KJ, Yu D. Neurotoxic Doses of Chronic Methamphetamine Trigger Retrotransposition of Identifier Element in Rat Dorsal Dentate Gyrus. Genes (Basel). Genes (Basel). 2017 Mar 6;8(3)
Grove TBa, Burghardt KJ, Kraal AZ, Dougherty RJ, Taylor SF, Ellingrod VL. Oxytocin Receptor (OXTR) Methylation and Cognition in Psychotic Disorders. Mol Neuropsychiatry. 2016 Oct;2(3):151-160. (adenotes equal effort)
Burghardt KJ, Goodrich JM, Dolinoy DC, EllingrodVL. Gene-specific DNA methylation may mediate atypical antipsychotic-induced insulin resistance. Bipolar Disord. 2016 Aug;18(5):423-32.
Gamal RS, Gardner KN, Burghardt KJ Pharmacogenomics Resources for the Psychiatric Practitioner. Current Psychiatry. Current Psychiatry. 2016 Sep;15(9):93-94.
Parker D, Sanders EJ, Burghardt KJ. Pharmacogenetics of Antiepileptic Drugs: A Brief Review. Mental Health Clinician. 2016 Jan; 6(1): 28-34.
Ellingrod VL, Grove TB, Burghardt KJ, Taylor SF, Dalack G. The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. Npj Schizophrenia. 2015 November; 1:15046.
Burghardt KJ, Thomas ST, Tutag-Lehr V. Off-label use of duloxetine for pediatric neuropathic pain. 2015 November; 5(6):277-283.
Burghardt KJ, Evans SJ, Wiese KM, Ellingrod VL. An Untargeted Metabolomics Analysis of Antipsychotic Use in Bipolar Disorder. Clinical and translational science. 2015; 8(5):432-40.
Burghardt KJ, Goodrich JM, Dolinoy DC, EllingrodVL. DNA methylation, insulin resistance and second generation antipsychotics (SGA) in bipolar disorder. Epigenomics. 2015; 7(3):343-52.
Bly MJ, Taylor SF, Dalack G, Pop-Busui R, Burghardt KJ, Evans SJ, McInnis MI, Grove TB, Brook RD, Zöllner SK, Ellingrod VL. Metabolic syndrome in bipolar disorder and schizophrenia: dietary and lifestyle factors compared to the general population. Bipolar Disord. 2014 May;16(3):277-88.
Burghardt K, Grove T, Ellingrod V. Endothelial nitric oxide synthetase genetic variants, metabolic syndrome and endothelial function in schizophrenia. J Psychopharmacol. 2014 Apr;28(4):349-56
Bostwick JR, Burghardt KJ, Choe HM, Deneke E, Fluent T. Opportunities to partner with clinical pharmacists in ambulatory psychiatry. Current Psychiatry 2014 July;13(7):23-29.
NIH K23 Patient-Oriented Career Development Award
Funding IC: NIDDK - K23DK118199
“Acutely Induced Insulin Resistance by Antipsychotic Medication in Healthy Volunteers: Impact of Skeletal Muscle Epigenomic and Proteomic Mechanisms”
Role: PI (75%)
American Association of Colleges of Pharmacy
Science of Teaching and Learning Grant
“Effects of Hands-On Personalized Genetic Testing in Pharmacogenetics Education”
Role: Primary Investigator (5%)
Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences Faculty Research Award Program (FRAP) Collaborative Grant
“The Role of Transposable Elements in Neurotoxic Effects of Chronic Methamphetamine”
Role: Co-Primary Investigator
National Institutes of Health Loan Repayment Program for Extramural Clinical Research
Funding IC: National Institute of Diabetes Digestive and Kidney Diseases (NIDDK)
“Mechanisms of antipsychotic-induced insulin resistance in the skeletal muscle”
NIH - L30 DK110823
Role: Primary Investigator
Completed
Wayne State University Eugene Applebaum College of Pharmacy and Health Sciences Faculty Research Award Program (FRAP) Collaborative Grant
“Insulin Resistance Induced by Antipsychotic Medication in the Absence of Obesity: Impact of Skeletal Muscle Protein Kinase-based Mechanisms”
Role: Primary Investigator (15%)
Brain & Behavior Research Foundation
NARSAD Young Investigator Grant
“Effects of FAAH Genotype on Fear-Related Brain Activation during Fear Extinction”
Role: Co-Investigator (5%)
Michigan Diabetes Research Center (MDRC)
P30 Pilot/Feasibility Grant
“Insulin Resistance Induced by Antipsychotic Medication in the Absence of Weight Gain: Impact of Skeletal Muscle Epigenetic and Protein Mechanisms”
NIH Grant 2P30-DK020572
Role: Primary Investigator
American College of Clinical Pharmacy
Futures Research Junior Investigator Grant
“Insulin Resistance Induced by Antipsychotic Medication in the Absence of Obesity: Impact of DNA Methylation and Lipids in the Skeletal Muscle”
Role: Primary Investigator
Wayne State University Office of the Vice President for Research.
Research Mentors Program for New Faculty
PIs: Yi and Burghardt
NIH: NIMH
Sex as a Biological Variable Supplement
“The Role of Sex in the Epigenetics of Antipsychotic-induced Metabolic Syndrome”
PI: Ellingrod
NIH R01 MH082784 S1
Role: Co-I.
Facilitate all sample preparation, analyses and data presentation. Publish results.
Recent Publications
NCBI
ORCiD
Burghardt KJ*, Howlett BH, Khoury A., Fern SM, Burghardt PR. Three Commonly Utilized Scholarly Databases and a Social Network Site Provide Different, but Related, Metrics of Pharmacy Faculty Publication. Publications 2020, 8(2), 18.
Burghardt KJ*, Khoury A, Msallaty Z, Yi Z, Seyoum B. Antipsychotic Medications and DNA Methylation in Schizophrenia and Bipolar Disorder: A Systematic Review. Pharmacotherapy. Accepted 1/24/2020.
Burghardt KJ*, Howlett BH, Fern SM, Burghardt PR. A Bibliometric Analysis of the Top 50 NIH-Funded Colleges of Pharmacy Using Two Databases. Research in Social and Administrative Pharmacy. 2019 Oct 9. pii: S1551-7411(19)30677-1.
Burghardt KJ*, Howlett BH, Sanders E, Dass SE, Msallaty Z, Mallisho A, Seyoum B, Yi Z. Skeletal Muscle DNA Methylation Modifications and Psychopharmacologic Treatment in Bipolar Disorder. European Neuropsychopharmacology. 2019 Oct 18. pii: S0924-977X(19)31700-6.
Kraal, AZ*, Moll AC, Arvanitis NR, Ward KM, Dougherty RJ, Grove TB, Burghardt KJ, Ellingrod VL. Metabolic Syndrome is Negatively Associated with Cognition among Endothelial Nitric Oxide Synthase (eNOS)-786C carriers in Schizophrenia-Spectrum Disorders. Journal of Psychiatric Research. 2019 Oct;117:142-147.
James R. Bagley, Kyle J. Burghardt, Ryan McManus, Irene S. Tobias, Bradley Howlett, Pablo B. Costa, Jared W. Coburn, Jose A. Arevalo, Moh H. Malek, and Andrew J. Galpin*. Epigenetic Responses To Acute Resistance Exercise In Trained Vs. Sedentary Men. Journal of Strength and Conditioning Research. In Press.
Burghardt KJ, Ward KM, Sanders E, Howlett BH, Seyoum B, Yi Z. Atypical Antipsychotics and the Human Skeletal Muscle Lipidome. Metabolites. 2018 Oct 13;8(4).
Bacon OM, Burghardt DR, Burghardt KJ. Management of pain in a patient taking naltrexone and needing an outpatient procedure. Current Psychiatry. Current Psychiatry. 2018 September;17(9):46-48.
Burghardt KJ, Goodrich JM, Line BN, EllingrodVL. The Influence of Metabolic Syndrome and Sex on the DNA Methylome in Schizophrenia. Int J Genomics. Volume 2018 (2018), Article ID 8076397, 12 pages.
Burghardt KJ, Seyoum B, Dass SE, Sandera E, Mallisho A, Yi Z. Association of Protein Kinase B (AKT) DNA Hypermethylation with Maintenance Atypical Antipsychotic Treatment in Patients with Bipolar Disorder. Pharmacotherapy. 2018 Apr;38(4):428-435.
Burghardt KJ, Seyoum B, Mallisho A, Burghardt PR, Kowluru RA, Yi Z. Atypical antipsychotics, insulin resistance and weight; a meta-analysis of healthy volunteer studies. Prog Neuropsychopharmacol Biol Psychiatry. 2018 Apr 20;83:55-63.
Burghardt KJ, Jaber LA. Haptoglobin Gene Polymorphisms and Diabetes Risk in the Arab-American Population. Submitted to Biomarkers in Medicine. Biomarkers in Medicine. Biomark Med. 2017 Nov;11(11):937-945.
Moszczynska A, Burghardt KJ, Yu D. Neurotoxic Doses of Chronic Methamphetamine Trigger Retrotransposition of Identifier Element in Rat Dorsal Dentate Gyrus. Genes (Basel). Genes (Basel). 2017 Mar 6;8(3)
Grove TBa, Burghardt KJ, Kraal AZ, Dougherty RJ, Taylor SF, Ellingrod VL. Oxytocin Receptor (OXTR) Methylation and Cognition in Psychotic Disorders. Mol Neuropsychiatry. 2016 Oct;2(3):151-160. (adenotes equal effort)
Burghardt KJ, Goodrich JM, Dolinoy DC, EllingrodVL. Gene-specific DNA methylation may mediate atypical antipsychotic-induced insulin resistance. Bipolar Disord. 2016 Aug;18(5):423-32.
Gamal RS, Gardner KN, Burghardt KJ Pharmacogenomics Resources for the Psychiatric Practitioner. Current Psychiatry. Current Psychiatry. 2016 Sep;15(9):93-94.
Parker D, Sanders EJ, Burghardt KJ. Pharmacogenetics of Antiepileptic Drugs: A Brief Review. Mental Health Clinician. 2016 Jan; 6(1): 28-34.
Ellingrod VL, Grove TB, Burghardt KJ, Taylor SF, Dalack G. The effect of folate supplementation and genotype on cardiovascular and epigenetic measures in schizophrenia subjects. Npj Schizophrenia. 2015 November; 1:15046.
Burghardt KJ, Thomas ST, Tutag-Lehr V. Off-label use of duloxetine for pediatric neuropathic pain. 2015 November; 5(6):277-283.
Burghardt KJ, Evans SJ, Wiese KM, Ellingrod VL. An Untargeted Metabolomics Analysis of Antipsychotic Use in Bipolar Disorder. Clinical and translational science. 2015; 8(5):432-40.
Burghardt KJ, Goodrich JM, Dolinoy DC, EllingrodVL. DNA methylation, insulin resistance and second generation antipsychotics (SGA) in bipolar disorder. Epigenomics. 2015; 7(3):343-52.
Bly MJ, Taylor SF, Dalack G, Pop-Busui R, Burghardt KJ, Evans SJ, McInnis MI, Grove TB, Brook RD, Zöllner SK, Ellingrod VL. Metabolic syndrome in bipolar disorder and schizophrenia: dietary and lifestyle factors compared to the general population. Bipolar Disord. 2014 May;16(3):277-88.
Burghardt K, Grove T, Ellingrod V. Endothelial nitric oxide synthetase genetic variants, metabolic syndrome and endothelial function in schizophrenia. J Psychopharmacol. 2014 Apr;28(4):349-56
Bostwick JR, Burghardt KJ, Choe HM, Deneke E, Fluent T. Opportunities to partner with clinical pharmacists in ambulatory psychiatry. Current Psychiatry 2014 July;13(7):23-29.