Research Description
PDZ-mediated macromolecular complexes in health and diseases; CXCR2 macromolecular signaling complex in vascular diseases (ischemia, angiogenesis), inflammation (neutrophil transmigration), and cancer biology (tumor metastasis and angiogenesis); Spatiotemporal dynamics of CXCR2 macromolecular signaling complex in living cells.
Techniques used in our research: molecular cloning, protein engineering and purification, biochemical assays, mammalian cell culture, live cell imaging, animal models (for cancer and inflammation), etc